Description

2-Chloro-3-Cyclopropylpyridine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular architecture, featuring a pyridine core substituted with both chloro and cyclopropyl groups, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the cyclopropyl moiety often contributes to enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals due to its rigid, aromatic structure.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-3-Cyclopropylpyridine
CAS No.	865664-04-6
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	3-Cyclopropyl-2-chloropyridine; 2-Chloro-3-cyclopropylpyridine; Pyridine, 2-chloro-3-cyclopropyl-; 865664-04-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Cyclopropylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We are committed to meeting the stringent requirements of GMP and ISO standards for advanced intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.