Description

2-Chloro-3-(Difluoromethyl)Pyridine is a high-purity, versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and difluoromethyl substituents, makes it an essential intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its halogenated pyridine core.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	2-Chloro-3-(Difluoromethyl)Pyridine
CAS No.	865663-96-3
Molecular Formula	C6H4ClF2N
Molecular Weight	163.55 g/mol
Synonyms	2-Chloro-3-(difluoromethyl)pyridine; 3-(Difluoromethyl)-2-chloropyridine; Pyridine, 2-chloro-3-(difluoromethyl)-; 865663-96-3; 2-Chloro-3-difluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Difluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.