Description

5-Fluoro-Thiazolo[5,4-B]Pyridin-2-Ylamine is a high-value heterocyclic organic compound featuring a fused thiazolopyridine core, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fluorinated structure makes it a key building block for modulating the biological activity, metabolic stability, and binding affinity of novel drug candidates. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted small molecule therapies.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic scaffold contribute to efficacy and environmental stability.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and protein-ligand interactions in biochemical assays.
• Material Science Precursor: Potential precursor for the synthesis of specialized organic electronic materials or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	5-Fluoro-Thiazolo[5,4-B]Pyridin-2-Ylamine
CAS No.	865663-86-1
Molecular Formula	C6H4FN3S
Molecular Weight	169.18 g/mol
Synonyms	2-Amino-5-fluorothiazolo[5,4-b]pyridine; 5-Fluorothiazolo[5,4-b]pyridin-2-amine; 865663-86-1; Thiazolo[5,4-b]pyridin-2-amine, 5-fluoro-; 5-Fluoro-2-aminothiazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-Thiazolo[5,4-B]Pyridin-2-Ylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from light. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.