Description

4-(2-Methoxyphenyl)-2-Methyl-6-(2-Thienyl)Nicotinonitrile is a high-value, multi-substituted nicotinonitrile derivative that serves as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex heterocyclic scaffolds, which are essential for developing novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical research and development (R&D) teams, particularly those focused on kinase inhibitors and other small-molecule therapeutics, are the primary industrial users of this specialized chemical.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for kinase-targeted therapies in oncology and inflammatory diseases.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new synthetic pathways and creating libraries of novel heterocyclic compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection products.
• Material Science: Investigated for the creation of organic electronic materials and ligands for catalytic systems due to its conjugated structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	4-(2-Methoxyphenyl)-2-Methyl-6-(2-Thienyl)Nicotinonitrile
CAS No.	865658-17-9
Molecular Formula	C18H14N2OS
Molecular Weight	306.38 g/mol
Synonyms	4-(2-Methoxyphenyl)-2-methyl-6-(thiophen-2-yl)nicotinonitrile; 2-Methyl-4-(2-methoxyphenyl)-6-(2-thienyl)-3-pyridinecarbonitrile; 6-(2-Thienyl)-4-(2-methoxyphenyl)-2-methyl-3-pyridinecarbonitrile; 4-(2-Methoxyphenyl)-2-methyl-6-(2-thienyl)pyridine-3-carbonitrile; 865658-17-9; Nicotinonitrile, 4-(2-methoxyphenyl)-2-methyl-6-(2-thienyl)-
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyphenyl)-2-Methyl-6-(2-Thienyl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.