Description

5-(Benzyloxy)-3-Bromo-2-Chloropyridine is a high-purity halogenated pyridine derivative, a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.
• Academic and Industrial R&D: A versatile reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	5-(Benzyloxy)-3-Bromo-2-Chloropyridine
CAS No.	864775-95-1
Molecular Formula	C₁₂H₉BrClNO
Molecular Weight	298.56 g/mol
Synonyms	3-Bromo-2-chloro-5-(phenylmethoxy)pyridine; 2-Chloro-3-bromo-5-benzyloxypyridine; 5-Benzyloxy-3-bromo-2-chloropyridine; 864775-95-1; Pyridine, 3-bromo-2-chloro-5-(phenylmethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 5-(Benzyloxy)-3-Bromo-2-Chloropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment. Our quality commitment aligns with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.