Description

(E)-Ethyl 3-(2-Bromo-4-(Bromomethyl)Phenyl)Acrylate CAS NO 864759-54-6 is a high-purity, multi-functional brominated aromatic acrylate ester, serving as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block. Its unique structure, featuring both bromine and a bromomethyl substituent on the phenyl ring, makes it an indispensable precursor for constructing complex molecules in medicinal chemistry and material science. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drugs, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing brominated charge-transport or emissive layer components.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalytic systems.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions due to its bromoaryl groups.
• Chemical Biology Probes: Employed in the design of activity-based probes and molecular tags for biochemical research.

Basic Information

Product Name	(E)-Ethyl 3-(2-Bromo-4-(Bromomethyl)Phenyl)Acrylate
CAS No.	864759-54-6
Molecular Formula	C₁₂H₁₂Br₂O₂
Molecular Weight	348.03 g/mol
Synonyms	Ethyl (E)-3-(2-Bromo-4-(bromomethyl)phenyl)acrylate; 2-Bromo-4-(bromomethyl)benzeneacrylic Acid Ethyl Ester; (E)-Ethyl 3-(2-Bromo-4-(Bromomethyl)Phenyl)-2-Propenoate; Acrylic Acid, 3-(2-Bromo-4-(bromomethyl)phenyl)-, Ethyl Ester, (E)-; Ethyl (E)-3-[2-Bromo-4-(bromomethyl)phenyl]prop-2-enoate; 864759-54-6; Ethyl 3-(2-Bromo-4-(Bromomethyl)Phenyl)Acrylate
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(2-Bromo-4-(Bromomethyl)Phenyl)Acrylate is manufactured under cGMP-like conditions, ensuring batch-to-batch consistency for critical R&D and scale-up applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles, supporting compliance with global regulatory standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling should be conducted under appropriate light conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.