Description

n-(2-Chloro-Pyridin-3-Yl)-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is a high-value boronic ester derivative, a key building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling Reactions: The primary application is as a boronic ester coupling partner with aryl or vinyl halides to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Incorporated into the design of molecular probes and tags for studying biological processes.

Basic Information

Product Name	n-(2-Chloro-Pyridin-3-Yl)-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide
CAS No.	864759-40-0
Molecular Formula	C18H20BClN2O3
Molecular Weight	358.63 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-chloropyridin-3-yl)benzamide; 2-Chloro-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]pyridin-3-amine; 864759-40-0; 4-Pinacolatoboron-N-(2-chloro-3-pyridyl)benzamide; Benzamide, N-(2-chloro-3-pyridinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-Pyridin-3-Yl)-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.