Description

1-[1,3]Dioxolan-2-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise and reliable synthesis is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific pyrazole-boronate structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a valuable handle for bioconjugation and the synthesis of molecular probes and sensors.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis of complex, bespoke organic molecules.
• Academic & R&D Laboratories: Utilized in methodological development and discovery chemistry for novel reaction pathways.

Basic Information

Product Name	1-[1,3]Dioxolan-2-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	864754-17-6
Molecular Formula	C13H21BN2O4
Molecular Weight	280.13 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((1,3-dioxolan-2-yl)methyl)-1H-pyrazole; 1-((1,3-Dioxolan-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(1,3-Dioxolan-2-ylmethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole; Pyrazole boronic ester pinacol derivative; (1-((1,3-Dioxolan-2-yl)methyl)-1H-pyrazol-4-yl)boronic acid pinacol ester; 864754-17-6; BRN 15904306
EINECS	Contact for details

Quality Control

Our production of 1-[1,3]Dioxolan-2-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including HPLC purity determination and NMR structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept sealed and opened only under anhydrous conditions to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.