Description

Methyl 5-Cyano-2-(Dimethoxymethyl)-6-(2,2,2-Trifluoroethylthio)Nicotinate is a high-purity, advanced pharmaceutical intermediate characterized by its multifunctional pyridine core. This compound matters for its critical role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those requiring a functionalized nicotinate scaffold.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique trifluoroethylthio and cyano groups.
• Material Science: Serves as a specialized monomer or additive in the research of advanced polymers and functional materials.
• Chemical Synthesis: Employed in organic synthesis as a versatile building block for creating libraries of compounds for high-throughput screening.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound discovery.

Basic Information

Product Name	Methyl 5-Cyano-2-(Dimethoxymethyl)-6-(2,2,2-Trifluoroethylthio)Nicotinate
CAS No.	864685-30-3
Molecular Formula	C14H15F3N2O4S
Molecular Weight	364.34 g/mol
Synonyms	Methyl 5-cyano-2-(dimethoxymethyl)-6-[(2,2,2-trifluoroethyl)sulfanyl]nicotinate; 2-(Dimethoxymethyl)-6-[(2,2,2-trifluoroethyl)thio]-5-cyanonicotinic Acid Methyl Ester; 5-Cyano-2-(dimethoxymethyl)-6-(2,2,2-trifluoroethylthio)nicotinic Acid Methyl Ester; Nicotinic acid, 5-cyano-2-(dimethoxymethyl)-6-[(2,2,2-trifluoroethyl)thio]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Cyano-2-(Dimethoxymethyl)-6-(2,2,2-Trifluoroethylthio)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.