Description

1-Boc-4-(4-Pyridin-2-Yl-Piperazin-1-Yl)-Piperidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly for creating molecules with specific receptor-binding profiles. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, especially within the central nervous system (CNS) and oncology fields.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• API Development: Serves as a crucial precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic and piperazine chemistry.

Basic Information

Item	Details
Product Name	1-Boc-4-(4-Pyridin-2-Yl-Piperazin-1-Yl)-Piperidine
CAS No.	864685-07-4
Molecular Formula	C19H30N4O2
Molecular Weight	346.47 g/mol
Synonyms	1-Boc-4-(4-(Pyridin-2-yl)piperazin-1-yl)piperidine; tert-Butyl 4-[4-(pyridin-2-yl)piperazin-1-yl]piperidine-1-carboxylate; 4-(4-Pyridin-2-yl-piperazin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[4-(2-pyridinyl)-1-piperazinyl]piperidine; BOC-Piperidine-Pyridylpiperazine Intermediate; 864685-07-4
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Pyridin-2-Yl-Piperazin-1-Yl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with ISO standards and supports development under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.