Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 3-Iodo-, Ethyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical and agrochemical discovery, where its unique pyrrolopyridine scaffold and iodine substituent enable precise molecular modifications. It is primarily utilized by medicinal chemists and process development scientists for constructing complex molecules, such as kinase inhibitors and other biologically active agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile probe or linker in the study of protein-ligand interactions and biochemical pathways.
• Material Science: Potential precursor for the development of organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized heterocyclic cores.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 3-Iodo-, Ethyl Ester
CAS No.	864681-19-6
Molecular Formula	C10H9IN2O2
Molecular Weight	316.10 g/mol
Synonyms	Ethyl 3-iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 3-Iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid ethyl ester; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 3-iodo-, ethyl ester; 864681-19-6; Ethyl 3-iodo-7-azaindole-5-carboxylate; 3-Iodo-7-azaindole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 3-Iodo-, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.