Description

1-(2-Chloro-6-Methoxypyridin-4-Yl)Ethanone is a high-purity, functionalized pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is essential for research and development chemists and process scale-up teams working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in heterocyclic chemistry targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom chemical synthesis (CDMO) services catering to the fine chemical and life science industries.

Basic Information

Product Name	1-(2-Chloro-6-Methoxypyridin-4-Yl)Ethanone
CAS No.	864674-09-9
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Chloro-6-methoxy-4-acetylpyridine; 4-Acetyl-2-chloro-6-methoxypyridine; 1-(2-Chloro-6-methoxy-4-pyridinyl)ethanone; 2-Chloro-4-acetyl-6-methoxypyridine; Ethanone, 1-(2-chloro-6-methoxy-4-pyridinyl)-; 4-Pyridinecarbonyl chloride, 2-chloro-6-methoxy- (related); 864674-09-9
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-6-Methoxypyridin-4-Yl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis steps. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.