Description

2-Bromo-4-(Chloromethyl)Pyridine is a versatile and highly functionalized pyridine derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its value lies in the simultaneous presence of reactive bromine and chloromethyl groups, enabling sequential and site-specific modifications to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Monomer or cross-linking agent for synthesizing specialty polymers and functionalized surfaces.
• Chemical Biology: Useful for bioconjugation and probe development due to its reactive handles for attaching fluorescent tags or other reporter groups.
• Custom Synthesis: Serves as a starting point for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	2-Bromo-4-(Chloromethyl)Pyridine
CAS No.	864460-68-4
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	4-(Chloromethyl)-2-bromopyridine; 2-Bromo-4-chloromethylpyridine; 2-Bromo-4-pyridinylmethyl chloride; (2-Bromo-4-pyridyl)methyl chloride; Pyridine, 2-bromo-4-(chloromethyl)-; 864460-68-4 (CAS); 2-Bromo-4-(chloromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Chloromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.