Description

2-(Chloromethyl)-6-Methoxypyridine Hydrochloride is a versatile and high-purity organic salt, serving as a critical building block in advanced chemical synthesis. Its value lies in its dual functional groups—the chloromethyl moiety and the methoxypyridine core—which enable precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine-based structure.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic & R&D Laboratories: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-(Chloromethyl)-6-Methoxypyridine Hydrochloride
CAS No.	864264-99-3
Molecular Formula	C7H9Cl2NO
Molecular Weight	194.06 g/mol
Synonyms	6-Methoxy-2-(chloromethyl)pyridine hydrochloride; 2-(Chloromethyl)-6-methoxypyridine HCl; 2-Chloromethyl-6-methoxypyridine hydrochloride; 6-Methoxy-2-pyridinemethanol, chloromethyl ether, hydrochloride; (6-Methoxypyridin-2-yl)methyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-Methoxypyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.