Description

Ethyl 2-Chloro-4-Methoxynicotinate is a high-purity synthetic intermediate of significant importance in modern organic synthesis. Its value lies in its functionalized pyridine core, which serves as a versatile building block for constructing more complex molecular architectures. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its bioactive nicotinate structure.
• Chemical Research & Development: Serves as a crucial precursor in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.
• Material Science: Potential intermediate for the synthesis of specialty chemicals, ligands for catalysis, and functionalized polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up production.

Basic Information

Product Name	Ethyl 2-Chloro-4-Methoxynicotinate
CAS No.	864229-51-6
Molecular Formula	C9H10ClNO3
Molecular Weight	215.63 g/mol
Synonyms	2-Chloro-4-methoxynicotinic Acid Ethyl Ester; Ethyl 2-Chloro-4-methoxypyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-chloro-4-methoxy-, ethyl ester; 864229-51-6; 2-Chloro-4-methoxy-nicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-4-Methoxynicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.