Description

2-Bromo-5,6-Dimethoxybenzothiazole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and methoxy substituents on the benzothiazole core, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the benzothiazole moiety can impart specific biological activity.
• Material Science Research: Serves as a precursor for the synthesis of organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-rich and modifiable structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create more complex biaryl and conjugated systems.
• Ligand and Catalyst Development: Utilized as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-5,6-Dimethoxybenzothiazole
CAS No.	864169-36-8
Molecular Formula	C9H8BrNO2S
Molecular Weight	274.14 g/mol
Synonyms	5,6-Dimethoxy-2-bromobenzothiazole; Benzothiazole, 2-bromo-5,6-dimethoxy-; 2-Bromo-5,6-dimethoxy-1,3-benzothiazole; 2-Bromo-5,6-dimethoxybenzothiazole; 864169-36-8
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 2-Bromo-5,6-Dimethoxybenzothiazole is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to meet the exacting standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.