Description

1,4,5,6-Tetrahydro-2-Methyl-6-Oxo-4-(4-Chlorophenyl)-3-Pyridinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate critical for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a reliable and consistent building block for research and production, ensuring downstream process integrity and final product quality. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within specialized chemical synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development and manufacturing of novel active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in multi-step organic synthesis for constructing complex heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Integral in the scaled-up production of specialty chemicals requiring high-purity, structurally defined intermediates.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and process development.
• Academic & Industrial Research: Utilized in chemical research for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1,4,5,6-Tetrahydro-2-Methyl-6-Oxo-4-(4-Chlorophenyl)-3-Pyridinecarboxylic Acid
CAS No.	864082-31-5
Molecular Formula	C14H14ClNO3
Molecular Weight	279.72 g/mol
Synonyms	4-(4-Chlorophenyl)-1,4,5,6-tetrahydro-2-methyl-6-oxo-3-pyridinecarboxylic acid; 4-(4-Chlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 1,4,5,6-tetrahydro-2-methyl-6-oxo-4-(4-chlorophenyl)-; 864082-31-5; 4-(p-Chlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,4,5,6-Tetrahydro-2-Methyl-6-Oxo-4-(4-Chlorophenyl)-3-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and reliable supply chain integrity makes us a trusted partner for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.