Description

5,7-Dichloro-1H-[1,6]Naphthyridin-4-One is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern synthetic chemistry. Its unique naphthyridinone scaffold, functionalized with chlorine atoms, makes it a valuable building block for constructing complex molecular architectures with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating specialized organic ligands or functional molecules used in catalysis or advanced materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for structure-activity relationship (SAR) studies.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for further functionalization.

Basic Information

Product Name	5,7-Dichloro-1H-[1,6]Naphthyridin-4-One
CAS No.	863785-66-4
Molecular Formula	C8H4Cl2N2O
Molecular Weight	215.04 g/mol
Synonyms	5,7-Dichloro-1H-[1,6]naphthyridin-4(1H)-one; 5,7-Dichloro-1,4-dihydro-[1,6]naphthyridin-4-one; 5,7-Dichloro-4-hydroxy[1,6]naphthyridine; 4(1H)-[1,6]Naphthyridinone, 5,7-dichloro-; 863785-66-4; 5,7-Dichloro-1H-1,6-naphthyridin-4-one
EINECS	Contact for details

Quality Control

Our 5,7-Dichloro-1H-[1,6]Naphthyridin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.