Description

Diethyl 2-[4-(Bromomethyl)Phenyl]Propane-1,3-Dioate is a high-purity brominated aromatic diester compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the reactive bromomethyl group, which facilitates efficient functionalization and chain extension, making it indispensable for constructing complex molecular architectures. This intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its aromatic backbone for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic cores used in electronic display technologies.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, thermal stability, or cross-linking density.
• Cross-Coupling Reactions: The bromomethyl moiety acts as an effective handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Organic Ligand Synthesis: Utilized in the preparation of chelating ligands for catalysis and material science applications.

Basic Information

Product Name	Diethyl 2-[4-(Bromomethyl)Phenyl]Propane-1,3-Dioate
CAS No.	863719-40-8
Molecular Formula	C15H19BrO4
Molecular Weight	343.22 g/mol
Synonyms	Diethyl 2-(4-(Bromomethyl)phenyl)malonate; 2-(4-(Bromomethyl)phenyl)propanedioic acid diethyl ester; 4-(Bromomethyl)benzylmalonic acid diethyl ester; Diethyl (4-(bromomethyl)phenyl)malonate; 863719-40-8; Diethyl 4-(Bromomethyl)benzylmalonate; Propanedioic acid, 2-[4-(bromomethyl)phenyl]-, 1,3-diethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.