Description

6-(4-Fluorophenyl)-Picolinic Acid is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and picolinic acid moiety impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Building block for advanced agrochemicals, such as herbicides and fungicides, leveraging the fluorophenyl group for enhanced efficacy.
• Precursor in material science for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Research chemical for academic and industrial R&D focused on structure-activity relationship (SAR) studies.
• Starting material for the synthesis of more complex fluorinated heterocycles and fine chemicals.

Basic Information

Product Name	6-(4-Fluorophenyl)-Picolinic Acid
CAS No.	863704-60-3
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-(4-Fluorophenyl)pyridine-6-carboxylic acid; 6-(4-Fluorophenyl)pyridine-2-carboxylic Acid; 2-Pyridinecarboxylic acid, 6-(4-fluorophenyl)-; Picolinic acid, 6-(4-fluorophenyl)-; 4-Fluoro-6-phenylpicolinic acid; 863704-60-3; 6-(p-Fluorophenyl)picolinic acid
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)-Picolinic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and commercial use. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.