Description

2-Pyridinecarboxylic Acid,5-Bromo-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1-Methylethyl Ester is a high-purity, multi-functional pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical building block and intermediate in the development of complex molecules, offering a unique combination of a bromo substituent and a protected amino group for selective functionalization. It is primarily utilized by pharmaceutical research and agrochemical development teams requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological mechanisms.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	2-Pyridinecarboxylic Acid,5-Bromo-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1-Methylethyl Ester
CAS No.	863444-51-3
Molecular Formula	C15H19BrN2O4
Molecular Weight	371.23 g/mol
Synonyms	5-Bromo-3-[(tert-butoxycarbonyl)amino]picolinic acid isopropyl ester; Isopropyl 5-bromo-3-[(tert-butoxycarbonyl)amino]picolinate; 3-[(Boc)amino]-5-bromopicolinic acid isopropyl ester; 5-Bromo-3-(Boc-amino)picolinic acid isopropyl ester; tert-Butyl N-(5-bromo-6-(isopropoxycarbonyl)pyridin-3-yl)carbamate; Isopropyl 5-bromo-3-((tert-butoxycarbonyl)amino)picolinate; Boc-3-Amino-5-bromopicolinic acid isopropyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinecarboxylic Acid,5-Bromo-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1-Methylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.