Description

2(1H)-Pyridinone, 5-[(4-Fluorophenyl)Methyl]- is a specialized fluorinated pyridinone derivative, a high-value intermediate in modern synthetic chemistry. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique fluorinated aromatic-pyridinone scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorophenyl moiety enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specific fluorinated heterocycle.

Basic Information

Product Name	2(1H)-Pyridinone, 5-[(4-Fluorophenyl)Methyl]-
CAS No.	863443-01-0
Molecular Formula	C12H10FNO
Molecular Weight	203.21 g/mol
Synonyms	5-[(4-Fluorophenyl)methyl]pyridin-2(1H)-one; 5-(4-Fluorobenzyl)-2(1H)-pyridinone; 5-(4-Fluorobenzyl)-2-hydroxypyridine; 5-(p-Fluorobenzyl)-2-pyridone; 2-Hydroxy-5-[(4-fluorophenyl)methyl]pyridine; 5-(4-Fluorobenzyl)-1H-pyridin-2-one; 863443-01-0
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Pyridinone, 5-[(4-Fluorophenyl)Methyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D and scale-up applications. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.