Description

1-Pyrrolidinecarboxylic Acid, 2-(Nitromethyl)-, Methyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its unique pyrrolidine-nitromethyl structure.
• Chiral Auxiliary & Ligand Precursor: Serves as a starting material for the preparation of chiral catalysts and ligands used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry for constructing proline-like scaffolds and peptidomimetic compounds to modulate biological activity.
• Fine Chemical Production: Acts as a versatile building block for the manufacture of complex, high-value specialty chemicals.
• Academic & Industrial R&D: Essential for exploratory chemistry in both academic institutions and corporate R&D laboratories focused on heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxylic Acid, 2-(Nitromethyl)-, Methyl Ester
CAS No.	863115-51-9
Molecular Formula	C7H12N2O4
Molecular Weight	188.18 g/mol
Synonyms	Methyl 2-(nitromethyl)pyrrolidine-1-carboxylate; 1-(Methoxycarbonyl)-2-(nitromethyl)pyrrolidine; 2-Nitromethyl-1-pyrrolidinecarboxylic acid methyl ester; Pyrrolidine-1-carboxylic acid, 2-(nitromethyl)-, methyl ester; Proline derivative, nitromethylated; 1-Carbomethoxy-2-(nitromethyl)pyrrolidine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 2-(Nitromethyl)-, Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.