Description

2-{1,4-Dioxaspiro[4.5]Decan-8-Ylamino}Ethan-1-Ol is a specialized organic compound featuring a spirocyclic ketal-protected ketone moiety linked to an ethanolamine chain, making it a valuable protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of functional groups and protecting sensitive carbonyl functionalities during complex multi-step reactions. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the synthesis of complex drug candidates, particularly those requiring spirocyclic or ketone-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the spirocyclic structure contributes to biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural products, macrocycles, and specialty chemicals.
• Material Science Research: Acts as a precursor for functional polymers or ligands in catalyst systems, leveraging its amine and hydroxyl functionalities.
• Chemical Biology Probes: Utilized in the development of molecular probes and linkers due to its reactive amino and alcohol groups, which can be further derivatized.

Basic Information

Product Name	2-{1,4-Dioxaspiro[4.5]Decan-8-Ylamino}Ethan-1-Ol
CAS No.	862730-43-6
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	8-(2-Hydroxyethylamino)-1,4-dioxaspiro[4.5]decane; 2-[(1,4-Dioxaspiro[4.5]decan-8-yl)amino]ethanol; 1,4-Dioxaspiro[4.5]decan-8-amine, N-(2-hydroxyethyl)-; 2-(1,4-Dioxaspiro[4.5]decan-8-ylamino)ethanol; 2-[(8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)amino]ethanol (tautomer); Spirocyclic ketal-protected amino alcohol; 8-Amino-1,4-dioxaspiro[4.5]decane-8-ethanolamine
EINECS	Contact for details

Quality Control

Our 2-{1,4-Dioxaspiro[4.5]Decan-8-Ylamino}Ethan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and process development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.