Description

2-(Propan-2-Yloxy)Pyridine-4-Carbonitrile is a versatile pyridine derivative and a key chemical intermediate characterized by its nitrile and ether functional groups. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	2-(Propan-2-Yloxy)Pyridine-4-Carbonitrile
CAS No.	862507-32-2
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	4-Cyano-2-isopropoxypyridine; 2-Isopropoxyisonicotinonitrile; 2-Isopropoxy-4-pyridinecarbonitrile; 2-(1-Methylethoxy)-4-pyridinecarbonitrile; 4-Pyridinecarbonitrile, 2-(1-methylethoxy)-; Isopropyl 4-cyano-2-pyridyl ether; 2-Isopropoxypyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-(Propan-2-Yloxy)Pyridine-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.