Description

Ethyl 5-Amino-2-Chloropyridine-4-Carboxylate is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and ester functional groups adjacent to a chlorinated pyridine ring, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	Ethyl 5-Amino-2-Chloropyridine-4-Carboxylate
CAS No.	862314-10-1
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	5-Amino-2-chloro-4-pyridinecarboxylic acid ethyl ester; Ethyl 5-amino-2-chloroisonicotinate; 2-Chloro-5-aminopyridine-4-carboxylic acid ethyl ester; 4-Carbethoxy-2-chloro-5-aminopyridine; 862314-10-1; 5-Amino-2-chloropyridine-4-ethyl carboxylate; 2-Chloro-5-amino-4-(ethoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 5-Amino-2-Chloropyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.