Description

1H-Imidazo[4,5-B]Pyridine,2-[[(2,5-Dimethylphenyl)Methyl]Thio]- is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core with a substituted thioether side chain. This specific molecular architecture makes it a critical intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams who require precise, high-purity building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, or photoactive materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and medicinal chemistry programs.
• Custom Synthesis: A starting material for the contract manufacturing of more complex, proprietary molecules for clients in the life sciences sector.

Basic Information

Product Name	1H-Imidazo[4,5-B]Pyridine,2-[[(2,5-Dimethylphenyl)Methyl]Thio]-
CAS No.	862194-33-0
Molecular Formula	C15H15N3S
Molecular Weight	269.36 g/mol
Synonyms	2-[[(2,5-Dimethylphenyl)methyl]thio]-1H-imidazo[4,5-b]pyridine; 2-((2,5-Dimethylbenzyl)thio)-1H-imidazo[4,5-b]pyridine; 1H-Imidazo[4,5-b]pyridine, 2-[[(2,5-dimethylphenyl)methyl]thio]-; 862194-33-0; 2-[(2,5-Dimethylbenzyl)sulfanyl]-1H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazo[4,5-B]Pyridine,2-[[(2,5-Dimethylphenyl)Methyl]Thio]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediates, and specifications can be aligned with client-specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.