Description

11H-Pyrido[2,1-b]quinazolin-11-one, 6,7,8,9-tetrahydro-4-hydroxy-6-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, (6E)- is a complex heterocyclic compound belonging to the pyrido-quinazolinone class, valued for its unique structural framework. This compound is significant as a versatile advanced pharmaceutical intermediate and a key scaffold in medicinal chemistry research for developing novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Organic Synthesis: Utilized in academic and industrial research for constructing complex polycyclic heterocyclic systems.
• Biochemical Tool Compound: Investigated for modulating specific biological pathways in preclinical research.

Basic Information

Item	Detail
Product Name	11H-Pyrido[2,1-b]quinazolin-11-one, 6,7,8,9-tetrahydro-4-hydroxy-6-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, (6E)-
CAS No.	862080-94-2
Molecular Formula	C22H20N2O5
Molecular Weight	392.41 g/mol
Synonyms	(6E)-6-[(4-Hydroxy-3,5-dimethoxyphenyl)methylene]-6,7,8,9-tetrahydro-4-hydroxy-11H-pyrido[2,1-b]quinazolin-11-one; 6-((4-Hydroxy-3,5-dimethoxyphenyl)methylene)-6,7,8,9-tetrahydro-4-hydroxy-11H-pyrido[2,1-b]quinazolin-11-one; 862080-94-2; Pyrido[2,1-b]quinazolinone derivative; Tetrahydro-11H-pyrido[2,1-b]quinazolin-11-one
EINECS	Contact for details

Quality Control

Our 11H-Pyrido[2,1-b]quinazolin-11-one derivative is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air and moisture during use.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.