Description

2-Methyl-4-Pyridineboric Acid Hcl CAS NO 861905-97-7 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted pyridine motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical organoboron reagent for palladium-catalyzed carbon-carbon bond formation to create complex biaryl systems.
• Ligand and Catalyst Development: A precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways and molecular libraries.
• Material Science: Potential monomer or building block for constructing organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	2-Methyl-4-Pyridineboric Acid Hcl
CAS No.	861905-97-7
Molecular Formula	C7H10BClNO2
Molecular Weight	187.42 g/mol
Synonyms	(2-Methylpyridin-4-yl)boronic acid hydrochloride; 4-Borono-2-methylpyridine hydrochloride; 2-Methyl-4-pyridinylboronic acid HCl; 2-Methyl-4-pyridineboronic acid hydrochloride; 4-(Boronyl)-2-methylpyridine hydrochloride; 2-Methylisonicotinic acid boronic ester hydrochloride (related); 4-Pyridineboronic acid, 2-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Pyridineboric Acid Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.