Description

1H-Imidazo[4,5-B]Pyridine,6-Chloro-2-[[[3-(Trifluoromethyl)Phenyl]Methyl]Thio]- is a high-value, synthetically versatile heterocyclic compound featuring a fused imidazopyridine core with a chlorinated pyridine ring and a trifluoromethylphenylthioether side chain. This molecular architecture makes it a critical pharmaceutical intermediate for the development of novel active ingredients, particularly in therapeutic areas requiring targeted bioactivity. It is primarily sought by research organizations, contract development and manufacturing organizations (CDMOs), and advanced pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science Precursor: Acts as a specialized monomer or ligand in the creation of advanced organic electronic materials or metal-organic frameworks (MOFs).
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Contract Synthesis & Custom Manufacturing: Supplied to CDMOs for scale-up and cGMP production of client-specific molecules.

Basic Information

Product Name	1H-Imidazo[4,5-B]Pyridine,6-Chloro-2-[[[3-(Trifluoromethyl)Phenyl]Methyl]Thio]-
CAS No.	861639-21-6
Molecular Formula	C15H9ClF3N2S
Molecular Weight	341.76 g/mol
Synonyms	6-Chloro-2-(((3-(trifluoromethyl)phenyl)methyl)thio)-1H-imidazo[4,5-b]pyridine; 6-Chloro-2-[[[3-(trifluoromethyl)phenyl]methyl]thio]-1H-imidazo[4,5-b]pyridine; 1H-Imidazo[4,5-b]pyridine, 6-chloro-2-[[[3-(trifluoromethyl)phenyl]methyl]thio]-; 861639-21-6; 6-Chloro-2-((3-(trifluoromethyl)benzyl)thio)-1H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) are available upon request, and we support development projects with custom purity grades, including research and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Research Grade)
Purity (HPLC)	≥ 98.0% (Advanced Grade)
Purity (HPLC)	≥ 99.0% (Custom Grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.