Description

6-Cyclopropyl-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile is a high-value, multi-functional heterocyclic building block featuring a cyclopropyl group and a trifluoromethyl substituent. This compound is critical for research and development in advanced organic synthesis, where its unique structure enables the creation of novel molecular architectures with tailored properties. It is primarily sought after by pharmaceutical and agrochemical R&D teams for use as a key intermediate in the synthesis of active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Research: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the cyclopropyl and trifluoromethyl groups.
• Material Science Precursor: Used in the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronic devices.
• Chemical Biology Probe: Employed in medicinal chemistry to develop tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences industry.

Basic Information

Product Name	6-Cyclopropyl-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile
CAS No.	861212-38-6
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	6-Cyclopropyl-4-(trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-6-cyclopropyl-4-(trifluoromethyl)-2(1H)-pyridinone; 6-Cyclopropyl-4-(trifluoromethyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 2-Hydroxy-6-cyclopropyl-4-(trifluoromethyl)nicotinonitrile; 1,2-Dihydro-6-cyclopropyl-2-oxo-4-(trifluoromethyl)-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.