Description

2-Chloro-5-[(4-Methylpiperidin-1-Yl)Methyl]Pyridine is a high-purity, advanced pharmaceutical intermediate with a distinct piperidine-pyridine hybrid structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Synthesis: Acts as a building block for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Chloro-5-[(4-Methylpiperidin-1-Yl)Methyl]Pyridine
CAS No.	861211-48-5
Molecular Formula	C12H17ClN2
Molecular Weight	224.73 g/mol
Synonyms	2-Chloro-5-((4-methylpiperidin-1-yl)methyl)pyridine; 1-(5-Chloropyridin-2-yl)methyl-4-methylpiperidine; 2-Chloro-5-[(4-methyl-1-piperidinyl)methyl]pyridine; 861211-48-5; 2-Chloro-5-(4-methylpiperidin-1-ylmethyl)pyridine; Pyridine, 2-chloro-5-[(4-methyl-1-piperidinyl)methyl]-; 2-Chloro-5-((4-methylpiperidin-1-yl)methyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-[(4-Methylpiperidin-1-Yl)Methyl]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.