Description

Ethyl 2-Cyclobutyl-2-Oxoacetate is a specialized organic ester compound featuring a cyclobutyl keto-ester structure. This molecular architecture makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring a constrained cyclobutane ring system.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the cyclobutyl moiety can influence biological activity and selectivity.
• Organic Synthesis Building Block: Serves as a versatile precursor for further chemical transformations, including reductions, alkylations, and cyclization reactions to create complex heterocycles.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing unique ester-based aroma compounds with specific structural characteristics.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialized polymers with tailored thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new synthetic pathways.

Basic Information

Product Name	Ethyl 2-Cyclobutyl-2-Oxoacetate
CAS No.	861160-59-0
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	Ethyl Cyclobutylglyoxylate; 2-Oxo-2-cyclobutylacetic Acid Ethyl Ester; Ethyl Cyclobutyl Oxoacetate; Cyclobutylglyoxylic Acid Ethyl Ester; Ethyl α-Oxocyclobutanecarboxylate; Acetic acid, 2-cyclobutyl-2-oxo-, ethyl ester; Ethyl (cyclobutylcarbonyl)formate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyclobutyl-2-Oxoacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.