Description

Nicotinamide, 4-Cyano-5-Methoxy-6-Methyl- (4Ci) is a specialized, high-value nicotinamide derivative characterized by its unique cyano and methoxy substituents. This compound is a critical advanced intermediate in the synthesis of complex pharmaceutical molecules, particularly in the development of novel therapeutics. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its role in creating innovative active ingredients. The precise molecular architecture of this intermediate enables targeted modifications essential for modern drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in areas targeting metabolic and neurological pathways.
• Agrochemical Research: Used in the development of next-generation herbicides and plant growth regulators, leveraging its nicotinamide core structure.
• Biochemical Research: Serves as a precursor or reference standard in enzymatic studies and metabolic research due to its structural relationship to vitamin B3.
• Organic Synthesis: Employed by fine chemical manufacturers for the custom synthesis of complex, multi-functional organic molecules.

Basic Information

Item	Details
Product Name	Nicotinamide, 4-Cyano-5-Methoxy-6-Methyl- (4Ci)
CAS No.	861045-70-7
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	4-Cyano-5-methoxy-6-methylnicotinamide; 5-Methoxy-6-methyl-4-pyridinecarbonitrile-3-carboxamide; 3-Carbamoyl-5-methoxy-6-methyl-4-pyridinecarbonitrile; 4-Cyano-5-methoxy-6-methyl-3-pyridinecarboxamide; (4Ci)-Nicotinamide derivative; Advanced Nicotinamide Intermediate; Research Grade 4Ci-Nicotinamide
EINECS	Contact for details

Quality Control

Every batch of Nicotinamide, 4-Cyano-5-Methoxy-6-Methyl- (4Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.