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2-Amino-4-Bromo-3-Chloropyridine CAS NO 861024-02-4
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CAS No.:861024-02-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-4-Bromo-3-Chloropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its multifunctional reactivity, where the amino, bromo, and chloro substituents provide distinct handles for selective cross-coupling and substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecular architectures.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, leveraging its halogenated structure for bioactivity.
- Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
- Ligand and Catalyst Development: Employed to construct complex nitrogen-containing ligands for transition metal catalysis.
- Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
- Custom Synthesis and R&D: A versatile scaffold for contract research organizations and discovery chemists exploring new chemical spaces.
Basic Information
| Product Name | 2-Amino-4-Bromo-3-Chloropyridine |
| CAS No. | 861024-02-4 |
| Molecular Formula | C5H4BrClN2 |
| Molecular Weight | 207.46 g/mol |
| Synonyms | 4-Bromo-3-chloro-2-pyridinamine; 3-Chloro-4-bromo-2-aminopyridine; 2-Pyridinamine, 4-bromo-3-chloro-; 4-Bromo-3-chloropyridin-2-amine; 2-Amino-3-chloro-4-bromopyridine; 4-Bromo-3-chloro-2-aminopyridine; AB3CP |
| EINECS | Contact for details |
Quality Control
Every batch of 2-Amino-4-Bromo-3-Chloropyridine is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, to ensure the material meets the stringent requirements for pharmaceutical and fine chemical applications. Our quality commitment aligns with cGMP principles for advanced intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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