Description

Methyl (3-Bromophenyl)(Difluoro)Acetate is a high-purity, specialty fluorinated building block essential for advanced organic synthesis. This compound is valued for its unique difluoroacetate ester moiety attached to a brominated aromatic ring, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing difluoroalkyl groups into bioactive molecules.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the bromophenyl and difluoroacetate functionalities impart specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals with tailored electronic and physical properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on understanding and applying fluorination chemistry.

Basic Information

Product Name	Methyl (3-Bromophenyl)(Difluoro)Acetate
CAS No.	860771-96-6
Molecular Formula	C9H7BrF2O2
Molecular Weight	265.05 g/mol
Synonyms	Methyl 2-(3-Bromophenyl)-2,2-difluoroacetate; 2-(3-Bromophenyl)-2,2-difluoroacetic Acid Methyl Ester; (3-Bromophenyl)difluoroacetic Acid Methyl Ester; Methyl α,α-Difluoro-3-bromophenylacetate; Methyl 3-Bromo-α,α-difluorophenylacetate; Difluoro(3-bromophenyl)acetic Acid Methyl Ester; Methyl 2,2-Difluoro-2-(3-bromophenyl)acetate
EINECS	Contact for details

Quality Control

Every batch of Methyl (3-Bromophenyl)(Difluoro)Acetate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.