Description

Dimethyl 2-(5-Amino-2-Pyridinyl)Malonate is a high-purity, versatile chemical intermediate featuring a functionalized pyridine core with an amino group and a malonate ester moiety. This compound is critical for the synthesis of complex heterocyclic systems, enabling the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require a functionalized pyridine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing fused heterocycles and complex organic molecules via condensation and cyclization reactions.
• Chemical Biology Probes: Utilized in the development of fluorescent tags and molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	Dimethyl 2-(5-Amino-2-Pyridinyl)Malonate
CAS No.	860650-20-0
Molecular Formula	C11H12N2O4
Molecular Weight	236.22 g/mol
Synonyms	Dimethyl (5-Aminopyridin-2-yl)malonate; 2-(5-Amino-2-pyridinyl)malonic Acid Dimethyl Ester; 5-Amino-2-pyridylmalonic Acid Dimethyl Ester; Dimethyl 2-(5-Amino-2-pyridyl)malonate; (5-Aminopyridin-2-yl)propanedioic Acid Dimethyl Ester; Propanedioic acid, 2-(5-amino-2-pyridinyl)-, 1,3-dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(5-Amino-2-Pyridinyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.