Description

1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its fused pyrrolopyridine core structure makes it a valuable intermediate for constructing complex molecules with tailored biological and electronic properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysts, and other functional organic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and exploring novel chemical spaces.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for coupling reactions to create fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid
CAS No.	860496-20-4
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	3-Pyrrolo[3,2-b]pyridinecarboxylic acid; 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid; 7-Azaindole-3-carboxylic acid; 1H-7-Azaindole-3-carboxylic acid; Pyrrolo[3,2-b]pyridine-3-carboxylic acid; 3-Carboxy-1H-pyrrolo[3,2-b]pyridine; 3-(1H-Pyrrolo[3,2-b]pyridin-3-yl)carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.