Description

1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid Hydrochloride is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused pyrrolopyridine scaffold makes it a valuable intermediate for developing novel pharmacologically active compounds. This material is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the synthesis of complex heterocyclic molecules due to its reactive carboxylic acid and nitrogen-containing ring system.
• Agrochemical Research: Potential intermediate in the development of new herbicides or fungicides with novel modes of action.
• Material Science Precursor: Can be used in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid Hydrochloride
CAS No.	860363-17-3
Molecular Formula	C8H7ClN2O2
Molecular Weight	198.61 g/mol
Synonyms	3-Carboxy-1H-pyrrolo[3,2-b]pyridine hydrochloride; 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid, hydrochloride; 7-Azaindole-3-carboxylic acid hydrochloride; 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid HCl; 3-Pyrrolo[3,2-b]pyridinecarboxylic acid hydrochloride; 860363-17-3; 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.