Description

1-Acetyl-3-Cyano-7-Azaindole, also known as 1-Acetyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, is a high-value nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its core azaindole scaffold, functionalized with acetyl and cyano groups, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1-Acetyl-3-Cyano-7-Azaindole / 1-Acetyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile
CAS No.	860362-11-4
Molecular Formula	C10H7N3O
Molecular Weight	185.18 g/mol
Synonyms	1-Acetyl-7-azaindole-3-carbonitrile; 1-Acetyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 7-Azaindole-3-carbonitrile, 1-acetyl-; 1-Acetyl-3-cyano-1H-pyrrolo[2,3-b]pyridine; 3-Cyano-1-acetyl-7-azaindole; 1-Acetyl-3-cyano-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-Cyano-7-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for research and scale-up. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced pharmaceutical applications, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.