Description

4-Chloro-3-Fluoropicolinic Acid is a high-purity, halogenated picolinic acid derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in the development of advanced agrochemicals and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Agrochemical Intermediate: A key building block in the synthesis of novel herbicides and plant growth regulators, leveraging the bioactivity of the picolinate scaffold.
• Pharmaceutical Synthesis: Used as a versatile precursor for active pharmaceutical ingredients (APIs), especially those requiring fluorinated and chlorinated aromatic systems.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	4-Chloro-3-Fluoropicolinic Acid
CAS No.	860296-21-5
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	4-Chloro-3-fluoropyridine-2-carboxylic acid; 3-Fluoro-4-chloropicolinic acid; 2-Pyridinecarboxylic acid, 4-chloro-3-fluoro-; 4-Chloro-3-fluoro-2-pyridinecarboxylic acid; 860296-21-5; 4-Chloro-3-fluoro-2-picolinic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Fluoropicolinic Acid is manufactured and tested under a rigorous quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, with specifications typically meeting or exceeding 98.0% purity (HPLC). A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting critical parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.