Description

4-(8-Chloro-4-Cyano-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridin-11-Ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Acts as a core scaffold for the research and development of potential kinase inhibitor candidates.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological processes and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of bespoke, high-value compounds for client R&D.
• Academic Research: Used in university and institutional laboratories for exploratory research in organic synthesis and pharmacology.

Basic Information

Product Name	4-(8-Chloro-4-Cyano-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridin-11-Ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	860010-33-9
Molecular Formula	C23H20ClN3O2
Molecular Weight	405.88 g/mol
Synonyms	Ethyl 4-[(8-chloro-4-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)]piperidine-1-carboxylate; 860010-33-9; UNII-9J8K3A8U4Q; 9J8K3A8U4Q; Benzo[5,6]cyclohepta[1,2-b]pyridine-11(6H)-carboxylic acid, 8-chloro-4-cyano-5,6-dihydro-11-(1-(ethoxycarbonyl)-4-piperidinylidene)-; 4-(8-Chloro-4-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to strict in-process controls and analytical validation using techniques such as HPLC, NMR, and MS to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.