Description

(E)-3-(3-Chloro-4-Methoxyphenyl)-1-(4-Methylphenyl)-2-Propen-1-One is a high-purity, synthetic chalcone derivative characterized by its specific stereochemistry and functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic building block for research and development. It is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory, anticancer, and antimicrobial applications.
• Agrochemical Research: Used as a core structure for developing new pesticides and herbicides due to its bioactive chalcone scaffold.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Michael additions, and cyclization reactions to create complex heterocyclic compounds.
• Material Science Research: Investigated as a monomer or dopant for the development of organic semiconductors and non-linear optical (NLO) materials.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition and signal transduction pathways.
• Academic & Industrial R&D: Serves as a standard or starting material for method development and discovery chemistry in contract research organizations (CROs).

Basic Information

Product Name	(E)-3-(3-Chloro-4-Methoxyphenyl)-1-(4-Methylphenyl)-2-Propen-1-One
CAS No.	860000-28-8
Molecular Formula	C17H15ClO2
Molecular Weight	286.75 g/mol
Synonyms	(E)-1-(4-Methylphenyl)-3-(3-chloro-4-methoxyphenyl)prop-2-en-1-one; 3-Chloro-4-methoxy Chalcone Derivative; (E)-3-(3-Chloro-4-methoxyphenyl)-1-p-tolylprop-2-en-1-one; (E)-3-(3-Chloro-4-methoxyphenyl)-1-(4-methylphenyl)prop-2-en-1-one; p-Methyl Chalcone Chloro Methoxy Derivative; Chalcone, 3'-chloro-4'-methoxy-4-methyl-; 860000-28-8
EINECS	Contact for details

Quality Control

Our (E)-3-(3-Chloro-4-Methoxyphenyl)-1-(4-Methylphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.