Description

3-Carboxymethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, protected morpholine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing morpholine or piperazine scaffolds.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and protease inhibitors due to its carboxylic acid and protected ester functionalities.
• Ligand Synthesis: Serves as a precursor for chelating agents and ligands in catalysis and metal complexation studies.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Utilized in universities and research institutes for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Carboxymethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	859155-89-8
Molecular Formula	C11H19NO5
Molecular Weight	245.27 g/mol
Synonyms	tert-Butyl 3-(carboxymethyl)morpholine-4-carboxylate; 4-(tert-Butoxycarbonyl)-3-(carboxymethyl)morpholine; 3-Carboxymethyl-4-Boc-morpholine; Morpholine-4-carboxylic acid, 3-(carboxymethyl)-, 1,1-dimethylethyl ester; Boc-3-carboxymethylmorpholine; 1,1-Dimethylethyl 3-(carboxymethyl)-4-morpholinecarboxylate
EINECS	Contact for details

Quality Control

Our 3-Carboxymethyl-Morpholine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.