Description

Ethyl 2-(4-Fluoro-3-Nitrophenyl)Acetate is a high-purity, synthetically valuable organic building block characterized by its fluorinated aromatic ring and ester functionality. This compound is essential for advanced pharmaceutical and agrochemical research, serving as a key intermediate in the synthesis of complex molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom and nitro group are key pharmacophores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors, due to its electron-withdrawing nitro and fluorine substituents.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 2-(4-Fluoro-3-Nitrophenyl)Acetate
CAS No.	858972-16-4
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	Ethyl (4-Fluoro-3-nitrophenyl)acetate; 2-(4-Fluoro-3-nitrophenyl)acetic Acid Ethyl Ester; Acetic acid, 2-(4-fluoro-3-nitrophenyl)-, ethyl ester; Ethyl 4-Fluoro-3-nitrobenzeneacetate; (4-Fluoro-3-nitrophenyl)acetic Acid Ethyl Ester; NSC 796064; Ethyl α-(4-Fluoro-3-nitrophenyl)acetate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(4-Fluoro-3-Nitrophenyl)Acetate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) confirming identity, purity, and conformity to customer specifications. Our quality commitment ensures the material is suitable for demanding applications in GMP-aligned synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.