Description

4-Iodo-2-Pyridone CAS NO 858839-90-4 is a halogenated pyridone derivative serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, enabling the introduction of the iodine moiety and the pyridone scaffold into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Employed as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: Serves as a competent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to synthesize novel nitrogen-containing ligands for metal complexes used in catalysis.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	4-Iodo-2-Pyridone
CAS No.	858839-90-4
Molecular Formula	C5H4INO
Molecular Weight	220.99 g/mol
Synonyms	4-Iodopyridin-2(1H)-one; 4-Iodo-1H-pyridin-2-one; 2-Hydroxy-4-iodopyridine; 4-Iodo-2-hydroxypyridine; 4-Iodo-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Every batch of 4-Iodo-2-Pyridone is produced and tested under a strict quality management system. We provide material that meets high-purity standards suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.