Description

2-Amino-3-Chloromethyl Pyridine Hydrochloride is a high-purity, versatile pharmaceutical intermediate and organic building block. This compound is critical for the synthesis of complex molecules, offering a reactive chloromethyl group and a protected amino functionality for targeted chemical modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel compounds. Its consistent quality and reliable supply are essential for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its pyridine core structure.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating novel heterocyclic compounds and functional materials.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and coordination chemistry.
• Bioconjugation and Probe Synthesis: Useful for modifying biomolecules or creating fluorescent probes and diagnostic agents in life sciences.

Basic Information

Product Name	2-Amino-3-Chloromethyl Pyridine Hydrochloride
CAS No.	858431-27-3
Molecular Formula	C7H10Cl2N2
Molecular Weight	193.07 g/mol
Synonyms	3-(Chloromethyl)pyridin-2-amine hydrochloride; 2-Amino-3-(chloromethyl)pyridine HCl; 2-Pyridinamine, 3-(chloromethyl)-, hydrochloride; 3-Chloromethyl-2-aminopyridine hydrochloride; 2-Amino-3-(chloromethyl)pyridinium chloride
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloromethyl Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.