Description

Ethyl 4-Hydroxy-2-Methylnicotinate is a high-purity nicotinate derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly within the pharmaceutical sector. It is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical production, and fine chemical synthesis who require reliable, high-quality intermediates for scale-up and process optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with nicotinic acid or pyridine core structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, insecticides, and fungicides.
• Fine Chemical Production: Employed as a building block for creating specialty chemicals, dyes, and functional materials.
• Research & Development: Serves as a standard or starting material in academic and industrial laboratories for method development and novel compound discovery.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for metal-organic frameworks (MOFs) or catalytic systems.

Basic Information

Item	Details
Product Name	Ethyl 4-Hydroxy-2-Methylnicotinate
CAS No.	858430-60-1
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	4-Hydroxy-2-methylnicotinic acid ethyl ester; Ethyl 4-hydroxy-2-methylpyridine-3-carboxylate; 2-Methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid ethyl ester; 4-Hydroxy-2-methyl-3-pyridinecarboxylic acid ethyl ester; 3-Carbethoxy-4-hydroxy-2-methylpyridine; 4-Hydroxy-2-methylnicotinate ethyl ester; Ethyl 4-hydroxy-2-methyl-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-2-Methylnicotinate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and other relevant regulatory guidelines for intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.