Description

4-(Aminomethyl)Picolinonitrile CAS NO 858362-83-1 is a versatile and high-value chemical building block featuring both an aminomethyl group and a nitrile functionality on a pyridine core. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Ligand and Chelator Preparation: Serves as a starting material for creating complexing agents and ligands used in catalysis and metal ion sequestration.
• Heterocyclic Chemistry Research: An essential building block for constructing diverse nitrogen-containing heterocycles in medicinal and synthetic chemistry.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers and advanced organic materials.

Basic Information

Product Name	4-(Aminomethyl)Picolinonitrile
CAS No.	858362-83-1
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	4-(Aminomethyl)pyridine-2-carbonitrile; 2-Cyano-4-(aminomethyl)pyridine; 4-(Aminomethyl)-2-cyanopyridine; 2-Pyridinecarbonitrile, 4-(aminomethyl)-; 4-(Aminomethyl)picolinonitrile; 858362-83-1; (2-Cyano-4-pyridinyl)methanamine
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Picolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.