Description

1H-Pyrrolo[2,3-B]Pyridine, 3-(Methoxymethyl)-1-[Tris(1-Methylethyl)Silyl]- is a high-value, protected heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds to develop novel active pharmaceutical ingredients (APIs) and agrochemicals. Its primary utility lies in the pharmaceutical and agrochemical R&D sectors, where it serves as a key intermediate for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Reagent: Serves as a protected precursor for the introduction of the 1H-Pyrrolo[2,3-b]pyridine moiety into more complex molecular architectures.
• Material Science Research: Potential use in the development of organic electronic materials and specialty polymers due to its conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 3-(Methoxymethyl)-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	858117-06-3
Molecular Formula	C17H29N2O1Si1
Molecular Weight	305.51 g/mol
Synonyms	3-(Methoxymethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Triisopropylsilyl)-3-(methoxymethyl)-1H-pyrrolo[2,3-b]pyridine; 1-TIPS-3-methoxymethyl-1H-pyrrolo[2,3-b]pyridine; TIPS-Protected 3-Methoxymethyl-7-azaindole; 7-Azaindole, 3-(methoxymethyl)-1-[(triisopropylsilyl)]-; 858117-06-3; Pyrrolo[2,3-b]pyridine derivative, TIPS-protected.
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine, 3-(Methoxymethyl)-1-[Tris(1-Methylethyl)Silyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced intermediates, providing full traceability and documentation to meet the rigorous standards of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.